Anti-precision medicine

  1. Some patients may not end up with any options from the set of existing therapies.
  2. At its worst, precision medicine can result in bias. This can be especially true if the criteria for excluding certain patient populations from a therapy is based on prior medical history or demographic criteria.
Coral’s 3-step approach to anti-precision medicine
History of TNFi: From in vitro to in vivo and back again
  1. looking for ways to get to standalone therapies that achieve similar performance
  2. trying a similar approach on other mechanisms (ex: IL12/23)
  3. working with pharma partners on downstream development

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CEO@Coral: patient diversity + improving therapies. MIT PhD 2018: single cell seq + CRISPR (Perturb-seq, Shuffle-seq)

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Atray Dixit

Atray Dixit

CEO@Coral: patient diversity + improving therapies. MIT PhD 2018: single cell seq + CRISPR (Perturb-seq, Shuffle-seq)

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